Cholesterol in Human Body: Importance and Dosage

  • Florentina GÎRBOIU “Dunarea de Jos” University of Galati, Romania
  • Alina Crina MUREŞAN “Dunarea de Jos” University of Galati, Romania
Keywords: cholesterol, low-density lipoproteins (LDL), high-density lipoproteins (HDL), Cobas Integra 400 Plus

Abstract

For a healthy life, specialists recommend us to take care of what food we eat and to what extent we do it and how we approach a satisfying lifestyle. Cholesterol is not a bad thing, but often, in large quantities it becomes dangerous for human body. The medical world is faced with frequent changes in the concept of "normal values" of cholesterol, but also with a continuously developing pharmaceutical industry in this field, and the tendency is in this sense, towards an  individualized treatment. This aspect in presented in our paper, which aims to describe the role of cholesterol in the functioning of human body; preventing the occurrence of heart diseases due increasing the level of cholesterol in the body and creating a healthy lifestyle that can reduce cholesterol levels. The paper presents some case studies on laboratory investigations of values cholesterol that includes determinations, studying and the research of medical equipment (Cobas Integra 400 Plus analyser), but also the results obtained during practice in the medical analysis laboratory.

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References

[1]. Garban Z., Garban G., Nutriţia umană, vol. I, Probleme fundamentale, ed. 3-a, Editura Orizonturi Universitare, ISBN 973-638-091-2, Timişoa ra , 2003.
[2]. Billimoria J. D., Fahmy M. F., Jepson E. M., Maclagen N. F., The use of the esterified fatty acid index in the classification and quantitation of hyperlipoproteinaemia, Atherosclerosis, vol. 14, issue 3, p. 359-374, 1971.
[3]. ***. https://pubchem.ncbi.nlm.nih.gov/compound/5997, Biblioteca Națională de Medicină, Institutele Naționale de Sănătate din SUA, 2019.
[4]. Silbernagl S., Fiziologia omului, Editura Ca llisto, Bucureşti, 2017.
[5]. Lustig R., Metabolical, Editura Hodder & Stoughton, New York, USA, 2021.
[6]. Havel R. J., Rappaport E., Management of primary hyperlipidemia, New England Journal of Medicine, vol. 332, p. 1491-1498, 1995.
[7]. ***, https://ro.khanacademy.org/science/biology/macromolecules/lipids/a/lipids.
[8]. Manu R., Obesity and cardiovascular risk in children and adolescents, Indian Journal of Endocrinology Metabolism, vol. 16 (1), p. 13-19, 2012.
[9]. Marchesseau P. V., Colesterolul - Prieten Sau Dușman?, Colecția să nă ta te și conștiință , Editura Sens, 2019.
[10]. ***, https://www.csid.ro/sanatate/sanatate-health/colesterolbun-hdl-si-colesterol-rau-ldl- 10399596/.
[11]. Mach F., et al., Grupul de Lucru pentru diagnosticul şi tratamentul dislipidemiilor al Societăţii Europene de Cardiologie (ESC) şi al Societăţii Europene de Ateroscleroză (EAS), Ghidul Societăţii Europene de Cardiologie (ESC)/ Societăţii Europene de
Ateroscleroză (EAS) pentru diagnosticul şi tratamentul dislipidemiilor 2019: modificările lipidice în vederea reducerii riscului cardiovascular, Romanian Journal of Cardiology, vol. 30, no. 2, p. 263-357, 2020.
[12]. Kreisberg R. A., Oberman A., Lipids and atherosclerosis:lesson learned from randomized controlled trial of lipid lowering and other relevant studies, The Journal of Clinical Endocrinology and Metabolism, vol. 87 (2), p. 423-437, 2002.
[13]. Bezu G., Modificările electrocardiografice în infarct miocardic acut şi angor pectoral, https://medinsemiologie.usmf.md/sites/default/files/inlinefiles/Optional.ECG_.IMA_.Angor_.Ro_.a.V.Medicina.2021.pdf.
[14]. Ference B. A., et al., Effect of long-term exposure to lower low-density lipoprotein cholesterol beginningearly in life on the risk of coronary heart disease: a Mendelian randomization analysis, Journal of the American College of Cardiology, vol. 60, article 2631-9, 2012.
Published
2023-12-15
How to Cite
1.
GÎRBOIU F, MUREŞAN AC. Cholesterol in Human Body: Importance and Dosage. The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science [Internet]. 15Dec.2023 [cited 25May2024];46(4):56-2. Available from: https://www.gup.ugal.ro/ugaljournals/index.php/mms/article/view/6502
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